文章摘要
王晶,甘轶文,贺笑笑.血清C反应蛋白及补体C3水平与急性阑尾炎患儿预后相关性[J].中国医药导刊,2017,19(12):1296-1298.
血清C反应蛋白及补体C3水平与急性阑尾炎患儿预后相关性
Correlation between Serum C Reactive Protein and Complement C3 Levels and Prognosis in Children with Acute Appendicitis
投稿时间:2017-08-28  修订日期:2017-12-13
DOI:
中文关键词: 急性阑尾炎  C反应蛋白  补体C3  相关性
英文关键词: Acute appendicitis  C reactive protein  Complement C3  Correlation
基金项目:
作者单位E-mail
王晶 江苏省南京同仁医院 儿科 zhang7385463@163.com 
甘轶文 江苏省南京同仁医院 儿科  
贺笑笑 江苏省南京同仁医院 儿科  
摘要点击次数: 313
全文下载次数: 102
中文摘要:
      目的:探讨血清中C反应蛋白(CRP)和补体C3水平在急性阑尾炎患儿预后中的关系。方法:筛选我院收治确诊为急性阑尾炎的32例患儿以及28例健康儿童血液样本,检测血清CRP和C3水平。对相关的各检测结果分别进行Pearson直线相关性分析和Logistic回归分析。结果:急性阑尾炎患儿血清CRP升高(P<0.01),C3含量降低(P<0.01);随严重程度升高,CRP增加,C3降低。Pearson分析表明,CRP与C3表达呈负相关(P<0.05);Logistic分析表明,CRP和C3均与急性阑尾炎诊断具有显著相关性(P<0.01);ROC曲线分析,结果显示CRP和C3在诊断急性阑尾炎中均具有显著的价值(P<0.01)。结论:CRP与C3能够诊断儿童急性阑尾炎,评估发病严重程度,指导临床采取合理治疗措施,改善患儿预后。
英文摘要:
      Objective: To investigate the relationship between serum C reactive protein(CRP) and complement C3 levels and prognosis in children with acute appendicitis.Methods:Blood samples of 32 cases with acute appendicitis and 28 healthy children were selected in our hospital and the levels of serum CRP and C3 were determined. Pearson linear correlation analysis and Logistic regression analysis were performed for each test result.Results: CRP level was significantly increased (P<0.01) in children with acute appendicitis, and the content of C3 was significantly decreased (P<0.01). With the increase of severity, CRP level was significantly increased, and complement C3 levelssignificantly decreased. Pearson analysis showed that CRP and C3 expression were negatively correlated (P<0.05). Logistic analysis showed that CRP and C3 were both significantly associated with the diagnosis of acute appendicitis(P<0.01). ROC curve analysis showed that CRP and C3 in the diagnosis of acute appendicitis had significant value (P<0.01). Conclusion: CRP and C3 can be used to diagnose acute appendicitis in children, to assess the severity of the disease, and to guide clinical treatment to improve the prognosis.
查看全文   查看/发表评论  下载PDF阅读器