文章摘要
翟丹丹,刘建军,孔薇,梁海.1例奥曲肽治疗舒尼替尼所致化疗性腹泻的药学监护[J].中国医药导刊,2019,21(7):433-436.
1例奥曲肽治疗舒尼替尼所致化疗性腹泻的药学监护
A Case of Pharmaceutical Care of Octreotide in the Treatment of Chemotherapeutic Diarrhea Caused by Sunitinib
投稿时间:2019-04-25  修订日期:2019-06-17
DOI:
中文关键词: 舒尼替尼  奥曲肽  药物性腹泻  药学监护
英文关键词: Sunitinib  Octreotide  Drug-induced diarrhea  Pharmaceutical care
基金项目:
作者单位E-mail
翟丹丹 合肥市第二人民医院 亳州市人民医院 zhaidandan8@126.com 
刘建军 合肥市第二人民医院 亳州市人民医院  
孔薇 合肥市第一人民医院  
梁海 亳州市人民医院  
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中文摘要:
      目的:分享临床药师参与1例小肠间质瘤患者药物性腹泻治疗的临床药学实践经验与体会。方法:患者改用舒尼替尼化疗方案后出现腹泻,停药后腹泻好转,临床药师推断为舒尼替尼所致的药物性腹泻,在洛哌丁胺止泻失败的情况下,提出使用奥曲肽止泻,并对不良反应进行监护及用药宣教。结果:患者腹泻得到控制,未发生不良反应。结论:临床药师可通过药学监护有效降低药品不良反应,保障用药安全。
英文摘要:
      Objective: To share the clinical pharmacy practice experience of the clinical pharmacist participating in treatment 1 case of drug-induced diarrhea of small intestinal stromal tumor patient. Methods: The diarrhea occurred after the patient switched to sunitinib chemotherapy, and improved after the withdrawal of the drug. The clinical pharmacist concluded that the diarrhea was caused by sunitinib. When loperamide failed to stop diarrhea, octreotide was proposed to stop diarrhea, and adverse reactions were monitored and medication education was conducted. Results: The diarrhea was under control and no adverse reaction occurred. Conclusion: Clinical pharmacists can effectively reduce adverse drug reactions and ensure drug safety by pharmaceutcal care.
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